This course offers the attendee an opportunity to re-examine ‘gait’, ‘ambulation’, ‘walking’, ‘bipedalism’, and ‘locomotion’ by addressing the cortical coordination of the human limbs that are responsible for individual forward locomotor movement patterns. Neurological and physiological dominance is designed around introspective habituation and compensation, that reflects physical predominant hemispheric loading and cortical hemi-spatial flow. A comprehensive, and up to date, review of literature and research on cortical dominance and associated pre-existing dominance factors that define interlimb and intralimb interaction during forward movement of the body, is offered. Arm and leg control, and overall associated motor function of human swing, support and propulsion will be addressed through asymmetrical gravitational balance effort and anti-gravitational eccentric considerations. Both, arm and leg control, and function in human locomotion, will be dissected and described, as a novel introduction to integrated upper and lower extremity movement, and hemi-spatial awareness and hemi-chest activity will be outlined, for all phases of forward locomotor movement. Clinical recommendations for individual introspection of forward locomotor movement will be provided throughout the course. Eccentric control of functional cortical predominant patterned limitations on locomotor movement, along with multisystem guidelines for reweighting balance through limb use, will be provided through the use of PRI non-manual technique application.